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In September 2024, Swiss Re published in their annual report, “Many countries worldwide still report elevated death in their population today.” This impact appears independent of healthcare system or population health. In the pessimistic model, Swiss Re would expect excess deaths to continue for another decade. There is also likely a degree of excess mortality underreporting.

CFOs from other life insurance companies confirmed that experienced mortality rates are broadly in line with this report. A skyrocketing increase in disability claimants since 2020 is another puzzling factor why CEOs of insurance companies are facing major problems with their financial model. The growth in demand is much lower, and the number of people making claims is much higher than expected. Declining revenues may soon hit the corporate bottom line.

For the first time in 80 years, the stocks from insurer Centene Medicaid plummeted in July 2025 by 41% after the insurer had to withdraw its full financial guidance because previous estimates were way off.

The analysis from insurance companies is comparable with earlier reports from Phinance Technologies, which analyzed publicly available data from the US and UK using various methods. Other independent analysts observed similar trends.

In recent years, hundreds of peer–reviewed articles discuss excess mortality and adverse events of special interest in various countries of pandemic measurements and after Covid-19 vaccinations.

Boston University just published the all-cause mortality in the US as compared to other High-Income Countries and showed that excess death rates peaked in 2021 and declined in 2022 and 2023 but remained substantially higher than pre-pandemic rates, especially in the age group 25-44 years. Mortality among US adults aged 25-44 years was 2.6 times higher as compared to other High-Income Countries.

A recent opinion from Kakeya et al. describes a significant increase in excess deaths after repeated Covid-19 vaccinations. Japan is the country with the highest per capita rate of messenger ribonucleic acid mRNA vaccination doses in the world.

A systematic review on Covid-19 mechanisms of injury and death compiled with autopsy confirmation by a physician application suggests there is a likelihood of a causal link between Covid-19 vaccines and deaths.

While there are studies that conclude there is no significant increase in stillbirths when women were vaccinated with the Covid-19 mRNA vaccine during pregnancy, a study based on VAERS data shows a significant increase. Another, not yet peer-reviewed, study indicates that Covid-19 vaccination with dose 1 during weeks 8-13 of pregnancy was associated with 3.9 fetal losses above expected for every 100 exposed pregnancies.

A study in the Czech Republic on live births of vaccinated versus non-vaccinated women demonstrated a substantially lower successful conception rate among vaccinated women than for those who were not vaccinated. The fertility rate in the Czech Republic dropped from 1.85 births per 1,000 women in 2021 to 1.62 in 2022 and 1.45 in 2023. Births in the EU fell to 1.38 births per woman. Also the US reported a historically low birth rate in 2023. Many Western countries are facing a similar problem with dropping fertility rates as the health of young women declined during the pandemic and post-pandemic economic instability.

Furthermore, maternal mortality rates accelerated at an alarming rate, especially from 2019-2022 in the US and UK, mainly caused by cardiovascular problems. The sharp spike in maternal death could not be explained by older age. Pregnancy-related maternal deaths are getting worse. In the UK, suicide remains the leading cause of direct maternal death in the first postnatal year.

Pandemic measures resulted in a collapse of women’s health and income, especially for those with the lowest wages working in healthcare, social services, education, and retail. During this period, the number of female healthcare worker suicides and fatal overdoses increased. ‘When the health of those who look out for people’s health is at risk the whole population and economy are at risk.’

Furthermore, it is well known that women respond more strongly and may experience a higher risk for complications after vaccinations. An age and sex associated difference in immune cell population might explain this. Observations from vaccination trials in Guinea-Bissau suggest increased female-male mortality ratio associated with inactivated polio and diphtheria-tetanus-pertussis vaccine. There is precedent for the observation that infant girls experience increased mortality following receipt of vaccines. People in healthcare (80% women) have been recommended and sometimes mandated a yearly flu vaccine and several boosters with Covid vaccine. While not tested, a flu vaccine and Covid vaccine were mostly given at the same moment.

A recent British study among 1,745 healthcare workers showed booster vaccinations did not contribute to the protection of the healthcare workforce in a post-pandemic setting. The Covid-19 vaccination may even temporarily increase the likelihood of symptomatic infection and workday loss.

A study of a large cohort of 3805 healthcare workers in Sweden confirmed that adverse reactions after Covid 19 vaccination can lead to a substantial amount of missed work shifts that can cause organizational disturbances in staffing. Risks were found to differ by vaccine type and regimen used, age, and sex, with young female healthcare workers experiencing more adverse reactions. The recently published British and Swedish studies are in line with a few earlier studies.

Recommending a combined use of four vaccines that prior to use had not been tested together during pregnancy when the immune system is following a precious time clock for the survival of both mother and child has been a risky approach.

Clinical trials with the Covid mRNA vaccine during pregnancy have shown data with serious worries that should have been openly discussed with pregnant women. Moreover, long-term effects for both mother and child remain unknown.

After the Netherlands and the UK, the US only recently said that Covid-19 vaccines are no longer recommended for healthy people under the age of 65 years and pregnant women. Whereas Covid-19 vaccines are still recommended for immunocompromised people, unfortunately they might be more at risk for experiencing Covid-19 infections after booster immunizations.

Although a causal relation remains difficult, the effects of repeated mRNA vaccination in combination or shortly before or after other vaccinations and/or using (psychiatric) medicine need to be elucidated. Sex differences in cost-effective harm analysis will help future decision -making.

Last week Robert F Kennedy, Jr stopped financing 500 million subsidiaries for the mRNA vaccine platform. Also the director of the NIH Dr Jay Bhattacharya wrote an opinion piece for the Washington Post: “Why the NIH is pivoting away from mRNA vaccines.” As a vaccine for a broad public use mRNA technology has failed to earn public trust.

A Post-Pandemic Increase of Female Mortality

In nearly all populations, women live longer than men. The ubiquity of female survival advantage for all ages, even during famine or epidemics, when mortality is extraordinarily high is changing.

Unfortunately, there is limited information available on sex differences in excess mortality from major respiratory infectious diseases. A peer-reviewed study on the first wave of the Covid-19 pandemic in Italy observed that gender differences in excess risk of death existed, but with a nuanced and non-consistent picture. The general finding of this study is that males up to 75 have been suffering more excess deaths as compared to females.

However, this picture is less clear-cut at older ages when more women are living in nursing homes which during the Covid pandemic showed the highest mortality rates. A study from the Netherlands on sex differences in Covid-19 mortalities skipped the data from healthcare workers and people living in nursing homes (mostly females) to confirm that male sex is a predisposing factor for severe Covid-19 independent of age and comorbidities.

Some other studies and a recent study (preprint) suggest Covid-19 did not produce lasting shifts in pre-pandemic sex differences in mortality in High-Income Countries and did not change the fundamental dynamic of the sex mortality gap. The authors observed that the male disadvantage in the Covid-19 mortality based on absolute death counts was concentrated in the pre-vaccine phase and declined over time. Relative increases in mortality were often similar between sexes, and in some cases, greater among women.

Another study on excess mortality of 561 regions and 21 countries in Europe indicate that in many European regions, where drops in life expectancy were more moderate, more pronounced life expectancy losses were found for women. The authors suggest that the degree of mortality deterioration is not necessarily linked to biological sex.

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